Male infertility is in 50% of instances a cause of the infertility of a couple.
The success rate of treatment of male infertility, in particular of azoospermia, the lack of sperm, or of oligospermia, ‘too little sperm’, or damaged sperm, etc., with modern medical therapies, has been close to zero.
Thus, with progress of in-vitro-fertilization techniques, male infertility has become a substantially more serious problem than female infertility.
It is not surprising that fetal precursor cell transplantation has been tried in such desperate situations.
In our experience with a few patients with azoospermia the treatment by BCRO fetal cell transplantation alone had a very low success rate, but subsequently a technique was developed, that makes a scientific sense and should be tried in some well selected patients.
This protocol requires a full cooperation of an infertility clinic.
After a complete diagnostic evaluation BCRO fetal precursor cell transplantation is carried out in order to:
- stimulate the ‘hypothalamus – pituitary – testes axis’, as well as to,
- accomplish an immunomodulation if necessary, and to
- treat any other existing disease of a patient.
After a month or so patient’s ejaculation has to be collected every week for 4 weeks, and inspected for normal, mobile, spermatozoa. If any such spermatozoa are found, they have to be concentrated, and eventually frozen.
When a sufficient quantity of spermatozoa is accumulated, an artificial insemination is carried out, and repeated as necessary.
As a male is usually not happy with the idea that his child would not be really his, before electing to use a sperm of a donor for in-vitro-fertilization, a trial of the above method should be offered.
In female infertility there are situations in medical practice, when in-vitro-fertilization had not worked, and repeatedly so, for reasons that cannot be elucidated by even the most sophisticated diagnostic methods and testing.
Fetal precursor cell transplantation should be considered in such instances, followed in 4 weeks by another in-vitro-fertilization attempt.
Even though the medical reports about such approach are hard to find, this has been a well guarded secret of many gynecologists dealing with infertility long before in-vitro-fertilization came into existence.